Thanks or the update, Gordan. I thought Emory University was cutting edge with Dr. Dong Moon Shin, who does a lot of research with EGFR inhibitors, and others. They say folate, B12 supplementation is given to counter some of the effects for Alimta, Pemetrexed. I don't know many who take this, usually for lung cancer, but sure others would like to know what's available, and more info can probably be obtained on lung cancer blogs. Good luck with everything.