My initial consult with the MO suggested doing TPF induction sequence then standard chemo-radiation. The RO is barely inline on this stating there are no conclusive studies showing improved outcomes and fairly significant side effects. The HNC surgeon made a general recommendation to go for the most aggressive option as I am young and strong and likely to tolerate the max treatment regime.

I was leaning pretty heavily toward doing the TPF induction even after the RO consult but after more research including what I read here, I now am not so sure.

Apparently, TPF induction does indeed generate numerous side effects, some quite extreme. I searched to board and gleaned what I could and not convinced either way. In fact, seems like more posts on bad side effects instead of gliding through induction.

What is your experiences with TPF or even PF induction treatment?

Did you make it all the way?

Did they cut it short or reduce the dosage?

What side effects did you experience?

Thanks
Don


Don
Male, 57 - Great health except C
Dec '12
DX: BOT SCC T2N2bMx, Stage 4a, HPV+, multiple nodes
1 tooth out
Jan '13
2nd tooth out
Tumor Board -induction TPF (3 cycles), seq CRT
4-6/2013
CRT 70gr 2x35, weekly carbo150
ended 5/29,6/4
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