The one good thing about Erbitux is it is said to be better with non HPV related cancer such as your wife"s - though honestly the tumor being in her cheek the best and possible treatment is surgery. I say this because it's a quick recovery generally. And then you're done with a chance of a cure / more time together. plus really after three weeks she'll be done with everything since it normally takes 6 weeks to completely heal... Assuming its still local. Definitely beats running to the hospital weekly the chemo cocktails etc... Hugs...it's a tough decision.