My husband had the 6 smaller treatments. If it wasn't for the lymphedema and sleep apnea that I think is from the extra swelling since it came on almost overnight he would be doing great. Back to eating everything after going weeks without a bite and no dry mouth problems, doesn't need a water bottle as many. He wasn't really nauseated and didn't take much of the meds but did get sick maybe 10 times from choking up the gunk. For him the gunk was the worst side effect and he was happy the day he no longer needed a spit cup.