I keep an eye on Science Daily: it aggregates research from a fairly wide variety of sources. Progress is being made on personalized treatment, but it's an incredibly complex subject. On an individual level, a disease is hit and miss - but as knowledge increases, the PATTERN of disease (and patient genetics, health, etc.) that will respond well to a particular treatment becomes better defined.

A note on the NCCN guessline - if you read them closely, you will see that there are varying levels of agreement on the protocol options.