My husband made it through what we hope is the final 5-fu treatment without further incident. I realized how important it is to have a responsive treatment team. This incident happened in the evening after I returned from work. (does a crisis ever occur between 9-5?). Within minutes I was in touch with the on-call nurse who helped us to identify/fix what turned out to be a minor problem. I searched through the topics on this site and I haven't seen much written about 5-fu. My husband's thrush has returned and I suspect it's the 5-fu. Any ideas?