1. still not fully sure. Possible, but not probable. Most are
HPV-16. see vaccine info below.
2. May be possible distantly, but
HPV does not have field of cancererization, unlike tobacco caaused, which can effect the whole aero digestive track, and
HPV usually is site specific, with one area of involvement, not involving several other structires. I heard you develop an antibody once exposed. I guess you can be exposed to
HPV the same time in several anatomical areas?
3. Again, you may have an antibody after exposure to
HPV-16
4.
HPV does not have field of cancerizsation like smoking related does. it is more site specific, not invloving other sites at once, but metastases or spread is different, and cancer can go anywhere.
I have read information from John Hopkins, Current preventive vaccine stragedy is not effective for treaating existing infections or established
HPV-related disease, Treatment established disease requires activation of the cellular immune system, both CD4+and CD8+Tcells, which cane recogniize virus infected cells. There is a difference between precevntive vaccines and therapeutic vaccine straregies.
There is a safety study at John hopkins for
HPV DNA Vaccine, to help your body's immune system recognize
HPV-Infected and associated cancer cells to treat HNC patients.
http://clinicaltrials.gov/show/NCT01493154
