For your assumption about chronic irritation to be true, you would have to prove that chronic irritation causes a DNA mutation, that causes a malignancy. It would have to be consistently repeatable in a similar group of people. It is not. While chronic irritation causes cellular changes, it is not commonly known to cause mutanogenic ones. It certainly cause hyperplasia, and other defensive conditions in cells.

Brian, stage 4 oral cancer survivor. OCF Founder and Director. The first responsibility of a leader is to define reality. The last is to say thank you. In between, the leader is a servant.