Markus is right. in situ lesions are VERY localized and have not really invaded deeply into the tissue even. It is the earliest possible moment of a malignant lesion. Obviusly without invasion there is no metastasis


Brian, stage 4 oral cancer survivor. OCF Founder and Director. The first responsibility of a leader is to define reality. The last is to say thank you. In between, the leader is a servant.