Jim, there is not a connection. The cellular change which causes Barrett's (which by the way is precanerous condition and not cancer) is caused by repeated damage to the lining of the esophagus by the acids in your stomach, and is in actuality a defense mechanism to prevent further damage. The cancer that is associated with Barrett's is adenocarcinoma predominantly... spoken by someone who has been down this path. GERD, proton pump inhibitors, fundoplycation, Barrett's, adenocarcinoma, surgical removal, etc.