Welcome Rebecca, most everyone here is a survivor or caregiver to someone with squamous cell carcinoma, which can effect the mucous membrane in various areas of the head and neck, other anatomical sites, and your susters sound like the base of tongue or oral tongue, both which can be effected by SCC, but are in different areas, one in in the oral cavity, and other oropharynx, and sometimes treated differently. When you get further info, update your profile signature with testing, bio, members can better assist you . Was your sister's biopsy tested for HPV?

Good luck.