#53631 12-22-2004 04:47 PM | Joined: Feb 2004 Posts: 218 Gold Member (200+ posts) | OP  Gold Member (200+ posts)
Joined: Feb 2004 Posts: 218 | Hi,
I'm wondering whether any of you have been taking COX-2 inhibitor NSAIDs: Vioxx, Celebrex or Naproxen(Alleve) as part of a chemoprevention program and if so, whether you are considering stopping because of the recent adverse clinical results indicating that these COX-2 inhibitors may cause an increased chance of stroke or heart attack and that the risk increases with the doseage and amount of time the drug has been taken.
I'm currently taking 200 mg. of Celebrex daily which I started on the advice of my oncologist about a month before these recent stories about Celebrex went public. Thanks for any light you can shed on this queston - Sheldon
Dx 1/29/04, SCC, T2N0M0
Tx 2/12/04 Surgery, 4/15/04 66 Gy. radiation (36 sessions)
Dx 3/15/2016, SCC, pT1NX
Tx 3/29/16 Surgery
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#53632 12-23-2004 02:00 AM | Joined: Apr 2004 Posts: 482 "Above & Beyond" Member (300+ posts) | | "Above & Beyond" Member (300+ posts)
Joined: Apr 2004 Posts: 482 | Sheldon, I'm not taking them now, but I did during treatment. I used Vioxx for a few weeks to help with the pain. I would check with your doctor today, if I were you.
Regards, Kirk Georgia
Stage IV, T1N2aM0, right tonsil primary, Tonsilectomy 11/03, 35 rad/3cisplatin chemo, right neck dissection 1/04 - 5/04.
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#53633 12-23-2004 10:09 AM | Joined: Sep 2003 Posts: 1,244 Patient Advocate (1000+ posts) | | Patient Advocate (1000+ posts)
Joined: Sep 2003 Posts: 1,244 | Sheldon
I took Vioxx for 5 years, Celebrex since the Vioxx scare, (I have Lupus) my understanding of the lastest scare is it only applies if you have heart problems, so I will continue for the moment, maybe see the Doc after the holiday period.
Sunshine... love and hugs
Helen
SCC Base of tongue, (TISN0M0) laser surgery, 10/01 and 05/03 no clear margins. Radial free flap graft to tonsil pillar, partial glossectomy, left neck dissection 08/04
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#53634 12-29-2004 11:08 AM | Joined: Dec 2003 Posts: 2,606 Likes: 2 Patient Advocate (old timer, 2000 posts) | | Patient Advocate (old timer, 2000 posts)
Joined: Dec 2003 Posts: 2,606 Likes: 2 | Sheldon,
Sorry for the delayed response but I was taking Vioxx until it was pulled and then moved over to Bextra. I am not concerned and as Helen points out, the scare is mostly if you have heart problems already. The trials that are of concern showed a 2% rate of heart problems versus 1% for the control group.
I also noticed the Bextra does a great job on the jaw pain I have had since radiation.
Ed
SCC Stage IV, BOT, T2N2bM0
Cisplatin/5FU x 3, 40 days radiation
Diagnosis 07/21/03 tx completed 10/08/03
Post Radiation Lower Motor Neuron Syndrome 3/08.
Cervical Spinal Stenosis 01/11
Cervical Myelitis 09/12
Thoracic Paraplegia 10/12
Dysautonomia 11/12
Hospice care 09/12-01/13.
COPD 01/14
Intermittent CHF 6/15
Feeding tube NPO 03/16
VFI 12/2016
ORN 12/2017
Cardiac Event 06/2018
Bilateral VFI 01/2021
Thoracotomy Bilobectomy 01/2022
Bilateral VFI 05/2022
Total Laryngectomy 01/2023
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