I don't know if this is pertinent, but four years ago my husband went through a treatment protocol at the Mayo Clinic for his tongue base cancer that involved intra-arterial chemotherapy and concurrent radiation. The protocol is sometimes called RADPLAT, for radiation + platinum.

The chemo was administered through catheters inserted into blood vessels in the groin (like an angiogram) on each side, and snaked up to the tumor site. Then the tumor was given a huge blast of Cisplatin, followed by a neutralizing agent. He had four rounds of the chemo (once a week for four weeks) and six weeks of daily radiation. It was quite an ordeal, but he is still alive four years later!

This is probably old news, in terms of cancer research. Hopefully you can find something newer and better.

Barb