I use the flouride trays for about 10 minutes before bed (I read to take my mind off of the situation) and I use the Biotene toothpaste before. I haven't tried the Biotene mouthwash (even though my wife bought it for me it has sat in the medicine cabinet because you get sick and tired of all of the stuff you have to do what with pain pills, trays, antibiotics, pegs, etc, etc, etc, you have to say enough somewhere). I will try the mouthwash now, though, if you all say it is so good. Thanks, Kirk Georgia