The answer may be just as difficult to find as an elusive tree frog. I'm no authority for sure, but have read many, well more than many, abstracts and studies on osteoradionecrosis and HBOT, including having and reading the book, "Handbook on Hyperbaric Medicine" by Dr David Mathier, 2006 edition, and others, and never saw for life mentioned, although it's over 700 pages lol, and could have missed it. The only times were as I previously mentioned. I looked again, and it actually said, "Effects of Hyperbaric Oxygen are permanent." That's it, no footnotes or anything to work on.

I did find that HBOT is just as complex as radiation treatment. There are many indications for it, exclusions also, and has many biological and physiological effects on the patient. HBOT for Osteoradionecrosis management, basically helps the radiation damage by partial reversal of Hypocellularity, Hypovascularity, and Hypoxia, known as the three H's, Angiogenetic and Fibroblastic, and inhibits inflammation. These are just some, and it gets complex.

This morning I contacted the "Undersea and Hyperbaric Medical Society" , which seems to be one of the authorities on HBOT in the U.S., and spoke with the Executive Director, who is not a medical doctor. Much of it was as I thought, that HBOT is very complex, has many indications. and they don't know all the effects about it. He had said that one treatment often works, but each incident is different, as there are different areas that may need treatment, and some may need it twice, and is difficult to say if it's for life or not, through angiogenesis, and is really based on the individual. When I asked about where the Life idea or part of that came from and was told from Dr. Marx's studies, but he couldn't find the study when we were on the phone, but believe it may be the one I mentioned.

Next step is to look further into Dr. Robert Marx's studies, if not, maybe contact his office for direction. I was wanting to inquire about the stem cell treatment that's he's doing at the University of Miami for Osteoradionecrosis anyway.

I hope this helps anyone in their search.


10/09 T1N2bM0 Tonsil
11/09 Taxo Cisp 5-FU, 6 Months Hosp
01/11 35 IMRT 70Gy 7 Wks
06/11 30 HBO
08/11 RND PNI
06/12 SND PNI LVI
08/12 RND Pec Flap IORT 12 Gy
10/12 25 IMRT 50Gy 6 Wks Taxo Erbitux
10/13 SND
10/13 TBO/Angiograph
10/13 RND Carotid Remove IORT 10Gy PNI
12/13 25 Protons 50Gy 6 Wks Carbo
11/14 All Teeth Extract 30 HBO
03/15 Sequestromy Buccal Flap ORN
09/16 Mandibulectomy Fib Flap Sternotomy
04/17 Regraft hypergranulation Donor Site
06/17 Heart Attack Stent
02/19 Finally Cancer Free Took 10 yrs