Lily,

If the topic of participating in a trial is offered, think through the benefits vs the risks to you. Trials are using patients as guinea pigs of sorts.

In the case of deescalation trials, one arm may be to use the current standard of care protocols while the other arm tests using less rads or whatever. It is random who gets which treatment, so you need to decide if you are comfortable testing a new, unproven protocol.

Naturally, if nobody participated there would be no advances so it is a bit of a moral dilemma.

But as stated earlier, current treatment options are not influenced by HPV status.