During his treatment, my son also had to make an emergency trip to the hospital because of his tongue swelling up causing him difficulty breathing. They told him it was a reaction to some meds he was taking and gave him a shot of benedryl to stop the swelling. It's definitely best to check with the ENT and find out why this happened so you can avoid it in the future. Everyone is different in their reactions. Just make sure the doctors know everything that is going into your body, even vitamins.