Sadly we are seeing 3 distinct groups of SCC now:

1. HPV+ with the Primary almost exclusively in the Orophyrnx region. Tonsils and BOT;
2. HPV- with a history of tobacco use, Primary just about everywhere else and
3. HPV- with a non smoking history and same Primary as #2.

Both #'s 2 and 3 prove to be more aggressive and more prone to recurrence than HPV+.


David

Age 58 at Dx, HPV16+ SCC, Stage IV BOT+2 nodes, non smoker, casual drinker, exercise nut, Cisplatin x 3 & concurrent IMRT x 35,(70 Gy), no surgery, no Peg, Tx at Moffitt over Aug 06. Jun 07, back to riding my bike 100 miles a wk. Now doing 12 Spin classes and 60 outdoor miles per wk. Nov 13 completed Hilly Century ride for Cancer, 104 miles, 1st Place in my age group. Apr 2014 & 15, Spun for 9 straight hrs to raise $$ for YMCA's Livestrong Program. Certified Spin Instructor Jun 2014.