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Joined: Mar 2008
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Sandy

It's our lives at stake here. To cheer you up, it could be worse with your doctor with whom you could CLASH instead of just not CLICK . I was surprisingly amenable to my doctors suggested treatment plans the first time around. Now that it did not work, I am argumentative and basically cross examining them. In my usual charming way of course. You are on the right track to win


65 yr Old Frack
Stage IV BOT T3N2M0 HPV 16+
2007:72GY IMRT(40) 8 ERBITUX No PEG
2008:CANCER BACK Salvage Surgery
25GY-CyberKnife(5) 3 Carboplatin
Apaghia /G button
2012: CANCER BACK -left tonsilar fossa
40GY-CyberKnife(5) 3 Carboplatin

Passed away 4-29-13
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Sandy,
part of the reluctance may come from the fact that the therapy also takes its toll.
Radiation and chemo both have long term problems by themselves. They are very toxic they just happen to be a tad more toxic for cancer cells; the damage they cause may result in cancers of their own later on. If you get too aggressive, you may get acute problems and/or increase the chance of treatment related malignacies. So it is a delicate balance and it is a statistical proposition (both getting cancer and treating it), no 2 people are the same.
With respect to carbo vs cisplatin issue, they are thought to work similarly (alkylating/cross linking your DNA). From what I understand carboplatin is much less quickly excreted and they will give you a much higher dose. The one thing that may be relevant in your case is that carbo is not nephrotoxic in contrast to cisplatin which is. They may be concerned with damaging your kidneys.

hope that helps.

Markus



Last edited by Markus; 03-31-2009 06:00 AM. Reason: comma again! may remove it again later on...

Partial glossectomy (25%) anterior tongue. 4/6/07/. IMRT start @5/24/07 (3x) Erbitux start/end@ 5/24/07. IMRT wider field (30x) start 6/5/07. Weekly cisplatin (2x30mg/m2), then weekly carbo- (5x180mg/m2). End of Tx 19 July 07.
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As always Markus is clear as mud. LOL and BTW Markus, Liz did not specify capitols and my version was much better than yours. So there!


David

Age 58 at Dx, HPV16+ SCC, Stage IV BOT+2 nodes, non smoker, casual drinker, exercise nut, Cisplatin x 3 & concurrent IMRT x 35,(70 Gy), no surgery, no Peg, Tx at Moffitt over Aug 06. Jun 07, back to riding my bike 100 miles a wk. Now doing 12 Spin classes and 60 outdoor miles per wk. Nov 13 completed Hilly Century ride for Cancer, 104 miles, 1st Place in my age group. Apr 2014 & 15, Spun for 9 straight hrs to raise $$ for YMCA's Livestrong Program. Certified Spin Instructor Jun 2014.
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Ahh, David .....Capitols.....

Back at you smile



Partial glossectomy (25%) anterior tongue. 4/6/07/. IMRT start @5/24/07 (3x) Erbitux start/end@ 5/24/07. IMRT wider field (30x) start 6/5/07. Weekly cisplatin (2x30mg/m2), then weekly carbo- (5x180mg/m2). End of Tx 19 July 07.
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Actually Markus makes a lot of sense.
I will get a re-staging PET sometime next week, so I'll have more of a feel for where we're going. I believe Markus is right. As my doctor can no longer feel my tumer, being too aggessive too soon create more problems later.

Thank you for your sage advice
Sandy


Sandy 56, BOT SCC Biopsy 1/21/09 Stage 3, T3NXM0.
Finished 3 cycle induction chemotherapy 4/7/09. (Chisplatin, 5-fu and Texotere). Re-staged 4/20/09,(very successful.) Will start Carboplatin/radiation 2 Gy/5 days/7 weeks (Tomotherapy) starting May 4th. Finished 6/22/09.
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Thank you for the compliment, please consider that this is just my opinion.... I am not an oncologist nor MD for that matter and no one can be diagnosed over the net. This forum provides a great platform for ideas/experiences that you can take and discuss with your team.
My young MO also was initially proposing to continue with additional chemo after the radiation/concurrent chemo, and while I did want to get rid of the beast once and for all, there was no clear benefit/indication and some additional risks. This was discussed with the MO and in the end I did not go for it. Apparently, the fact that I was still "moving" after the treatment made him think.... hmm he can take some more!

Now the sage thing... makes me feel old, like Dumbledore ..... (watch out David I just might turn you into a frog!)

Cheers

M




Partial glossectomy (25%) anterior tongue. 4/6/07/. IMRT start @5/24/07 (3x) Erbitux start/end@ 5/24/07. IMRT wider field (30x) start 6/5/07. Weekly cisplatin (2x30mg/m2), then weekly carbo- (5x180mg/m2). End of Tx 19 July 07.
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Better than a Toad which can give you warts which are caused by HPV with a capital H P V.


David

Age 58 at Dx, HPV16+ SCC, Stage IV BOT+2 nodes, non smoker, casual drinker, exercise nut, Cisplatin x 3 & concurrent IMRT x 35,(70 Gy), no surgery, no Peg, Tx at Moffitt over Aug 06. Jun 07, back to riding my bike 100 miles a wk. Now doing 12 Spin classes and 60 outdoor miles per wk. Nov 13 completed Hilly Century ride for Cancer, 104 miles, 1st Place in my age group. Apr 2014 & 15, Spun for 9 straight hrs to raise $$ for YMCA's Livestrong Program. Certified Spin Instructor Jun 2014.
Joined: Jun 2007
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Nice to see you Markus. it seems like it's bveen a long while. Better get some mace Sandy LOL


Since posting this. UPMC, Pittsburgh, Oct 2011 until Jan. I averaged about 2 to 3 surgeries a week there. w Can't have jaw made as bone is deteroriating steaily that is left in jaw. Mersa is to blame. Feeding tube . Had trach for 4mos. Got it out April.
--- Passed away 5/14/14, will be greatly missed by everyone here
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