I was wondering if anyone else that has taken the amifostine injections sub Q in the tummy has experienced severe bone and joint pain everyday after the injections ? I refused my injection on Tuesday and the Doc now has me on hold for the rest of the week (I hope). He says this is a rare side effect of the injection. It causes really bad large bone pain and joint pain in almost every joint, fingers, toes, elbows, knees, hips, shoulders,ankles, wrist, even jaw. This kicks in about 1 hour after the injection and last up to 12 hours. Lab results show that my calcium levels are normal so no hypocalcemia.