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Joined: Jun 2015
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Cal508 Offline OP
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Joined: Jun 2015
Posts: 9
My 20 year old brother has recurring pre cancerous lesions over the past couple of years. All have been mild and a few moderate dysplasia. Is there anything we can do to keep this from turning into cancer. I can't help but feel like there is even though I don't think so. He does not drink or smoke. Please don't scare me and tell me if yours eventually turned into cancer. Thanks

Joined: Jun 2007
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Administrator, Director of Patient Support Services
Patient Advocate (old timer, 2000 posts)
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Patient Advocate (old timer, 2000 posts)

Joined: Jun 2007
Posts: 10,507
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Im sorry your brother is having a problem with the lesions coming back. One thing you said is the key to this... they are non-cancerous. Most dysplasia never turns into cancer but it frequently does return after its been removed.

SInce this site is all about oral cancer, its very possible you run into members who have had their dysplasia turn into cancer. Im sorry but that cant be avoided when posting on a forum dedicated to oral cancer.

Best wishes to your brother. Im hoping he never has to deal with his dysplasia turning cancerous.


Christine
SCC 6/15/07 L chk & by L molar both Stag I, age44
2x cispltn-35 IMRT end 9/27/07
-65 lbs in 2 mo, no caregvr
Clear PET 1/08
4/4/08 recur L chk Stag I
surg 4/16/08 clr marg
215 HBO dives
3/09 teeth out, trismus
7/2/09 recur, Stg IV
8/24/09 trach, ND, mandiblctmy
3wks medicly inducd coma
2 mo xtended hospital stay, ICU & burn unit
PICC line IV antibx 8 mo
10/4/10, 2/14/11 reconst surg
OC 3x in 3 years
very happy to be alive smile
Joined: Jun 2015
Posts: 9
Cal508 Offline OP
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Joined: Jun 2015
Posts: 9
Is there a more aggressive course of action that you know of besides laser, tissue removal, & abstaining from smoking and alcohol?

He still eats a normal college boy diet. But I'm so proud of him for coming home every weekend to fish in order to avoid the party scene.

So it is common for it to return? It has never returned in the same spot. It's always a different spot. Seems like something comes up about every 4 months

Joined: Jul 2012
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Patient Advocate (old timer, 2000 posts)
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Patient Advocate (old timer, 2000 posts)

Joined: Jul 2012
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I've heard of different treatments, studies for oral leukoplakia, including chemoprevention, through the years. I'm not sure what are currently active or still applicable in this area, but a few were with Photodynamic Therapy (PDT), Tarceva an epidermal growth factor receptor, and chemoprevention with Vitamin A, and other retinoids, Beta Carotene, vitamin E and Selenium, biochemoprevention and others.

Through the years, there were also a number of reports regarding certain foods, extracts, medicines that were said "may" be beneficial, not that I'm promoting any, in reducing incidents of some head and neck cancers, pre-malignancies, so many that I lost count, such as with coffee, green tea, mushrooms, broccoli, curcumin or tumeric, metformin, etc.

I do believe a healthy lifestyle with absence from smoking, alcohol, chewing tobacco and other carcinogens, may help too, and maintaining a healthy immune system, and avoiding getting sick may help too.

I can't seem to copy some reports I saved by email, but you can google them, and I'm sure you'll find a number of them.


10/09 T1N2bM0 Tonsil
11/09 Taxo Cisp 5-FU, 6 Months Hosp
01/11 35 IMRT 70Gy 7 Wks
06/11 30 HBO
08/11 RND PNI
06/12 SND PNI LVI
08/12 RND Pec Flap IORT 12 Gy
10/12 25 IMRT 50Gy 6 Wks Taxo Erbitux
10/13 SND
10/13 TBO/Angiograph
10/13 RND Carotid Remove IORT 10Gy PNI
12/13 25 Protons 50Gy 6 Wks Carbo
11/14 All Teeth Extract 30 HBO
03/15 Sequestromy Buccal Flap ORN
09/16 Mandibulectomy Fib Flap Sternotomy
04/17 Regraft hypergranulation Donor Site
06/17 Heart Attack Stent
02/19 Finally Cancer Free Took 10 yrs







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