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#194123 - 04/10/17 07:19 PM Enlarging Node During RAD  
Joined: Feb 2017
Posts: 66
sooner Offline
Supporting Member (50+ posts)
sooner  Offline
Supporting Member (50+ posts)

Joined: Feb 2017
Posts: 66
Has anyone else experienced the only identified cancer containing neck node that is decreasing steadily in response to treatment then begins to obviously, visually increase in size? The RO and MO both feel it is some kind of treatment response not disease spread or treatment failure. Said this can happen if there is a bleed near the node or other inflammatory responses in the node.

Wife to DP. DX SCC BOT 1/31/17
First treatment 2/27/2017 Cisplatin 3 times and IMRT
Last treatment 4/18/2017
Clear PET 7/13/2017
PEG removed 8/4/2017
#194125 - 04/10/17 10:03 PM Re: Enlarging Node During RAD [Re: sooner]  
Joined: Jul 2012
Posts: 3,099
PaulB Offline
Patient Advocate (old timer, 2000 posts)
PaulB  Offline
Patient Advocate (old timer, 2000 posts)

Joined: Jul 2012
Posts: 3,099
It's unusual for cancer to spread/increase during treatment, but It has happened to me, and was going to say it could be an inflammatory response, as I was told in my case, and was closely monitored. Radiation should shrink a tumor a certain percentage, and if that doesn't seem to occur, doctors can make certain decisions such watch and wait, change treatment or to do surgery. Also, radiation keeps working a number of weeks after treatment stops. One of mine was still enlarged, had two cancerous, that we waited 5 months after treatment to do a PET scan, which came back clear, at least that scan did. Others doctors may scan after 6 weeks when the usual wait time is 3 months or 12 weeks, so they can effectively deal with any reminiscent cancer, and have heard of scanning during treatment, but not sure if that was part of a clinical trial or reason the reason for scanning, such as one trial checking for tumor hypoxia by PET scan, and another type of infusion.

10/09 T1N2bM0 Tonsil
11/09 Taxotere Cisplation 5-FU 6 Months Hosp
01/11 35 IMRT 70Gy 7 Weeks
06/11 30 HBO
08/11 RND PNI
08/12 RND Pec Flap IORT 12 Gy
10/12 25 IMRT 50Gy 6 weeks Taxotere Erbitux
10/13 SND
10/13 TBO/Angiograph
10/13 RND Carotid Removed IORT 10Gy PNI
12/13 25 Proton Therapy 50Gy 6 weeks Carboplatin
11/14 All Teeth Extract 30 HBO
03/15 Sequestromy Buccal Flap ORN
09/16 Mandibulectomy Fibular Flap Sternotomy
04/17 Regraft hypergranulation Donor Site
06/17 Heart Attack Stent

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