Don,
1. I woudn't do it again. There are other less toxic options with the same outcome for
HPV oropharynx cancer, and just may be an overkill, pun intended. My response was different, beyond brutal, but my cancer was gone just from the 5 days TPF, that almost killed me, which I only was able to later find out after 9 months. Laying in a hospital bed for 6 months, in isolation, being told you're too sick to have anything done, let alone not be able to walk, was the worst. As such, that's why my cancer was able to spread, had more recurrences, 8, but each their own. One day I'll write about my experience.
2.
HPV-16 is the high risk
HPV variant, which is the type mostly associated with
HPV oropharyngeal cancer. To a lesser extent,
HPV 18. There are about 150
HPV types, some simple warts, and about 15 are high risk that can go on to cause cancer, in some, like ours.
http://oralcancernews.org/wp/study-...ncer-patients-to-vary-depending-on-site/3. Yes, being
HPV-16 positive, p16 positive ( tumor suppressor gene) in oropharyngeal cancer is good, but with other cancers being p16 positive is a negative factor, and reduces risk of survival.
4. Yes,
HPV negative is "usually" associated with smoking , drinking, with poorer outcome. Some
HPV seems to respond like smoking, drinking caused does, more aggressive.
http://www.news-medical.net/news/20...-positive-and-HPV-negative-patients.aspxI probably confused it more. The more I know the less I understand too