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The BCL2 marker???
#131740 03-21-2011 02:15 PM
Joined: Mar 2011
Posts: 130
Likes: 3
Portland, Maine
MaineWill Offline OP
Senior Member (100+ posts)
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MaineWill
Senior Member (100+ posts)

Joined: Mar 2011
Posts: 130
Likes: 3
Portland, Maine
So, I'm told that I have the BCL2 marker which lowers my cure rate over regular HPV+ tonsil cancer, and thet the chemo needs to be stronger than Erbitux. Also my cells were poorly differentiated? Can anyone expand on that please? Much thanks. Will

Lump in left side neck discovered Sept 2009
Misdiagnosed & FNA inconclusive
Large lymph node removed Nov. 2010 SCC and HPV16 pos
PET pointed tonsilectomy Feb. 2011
1ml tumor left side tonsil
Rads scheduled March 14th 2011. 2X36 GY's (72)
CarboTaxol once a week X 4 or 5 starting 4/5/11
No PEG
Re: The BCL2 marker???
MaineWill #131750 03-21-2011 03:24 PM
Joined: Dec 2010
Posts: 5,260
Likes: 3
Toronto canada
Cheryld Offline
"OCF Canuck"
Patient Advocate (old timer, 2000 posts)
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Cheryld
"OCF Canuck"
Patient Advocate (old timer, 2000 posts)

Joined: Dec 2010
Posts: 5,260
Likes: 3
Toronto canada
Hey... okay - I don't know what a BCL2 marker is - sorry... I wish I did.

Differentiation I can do. There are three types of differentiation - well, moderate, and poor. Well differentiated cells behave like normal cells almost, moderate a little different, poorly differentiated are the wild childs of the bunch. Then there can be well/moderate... etc...

Poorly differentiated can be more aggressive, I guess that's why they said the Erbitux won't be the chemo of choice. Perhaps they have a stronger different one.

I am not sure about the chemos... I am sure someone here can tell you possibly what else they may use, and what the BCL3 marker is about. I wish I could help more.

hope things went okay today...
many hugs to you... day five... 1/7 th of the way there...

Cheryl : Irritation - 2004 BX: 6/2008 : Inflam. BX: 12/10, DX: 12/10 : SCC - LS tongue well dif. T2N1M0. 2/11 hemigloss + recon. : PND - 40 nodes - 39 clear. 3/11 - 5/11 IMRT 33 + cis x2, PEG 3/28/11 - 5/19/11 3 head, 2 chest scans - clear(fingers crossed) HPV-, No smoke, drink, or drugs, Vegan

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