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Brian Hill #114330 03-20-2010 06:34 AM
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Gee, just when I thought this was an open ended musing on the past and I was about to jump in with saying whoa, what about the major contribution by German physician-scientist, Dr. Harald zur Hausen, 72, for his discovery of HPV, or the human papilloma virus causing cervical cancer,which won him the 2008 Nobel Prize in medicine. According to the New York Times: [quote]In 1983, Zur Hausen discovered the first HPV, type 16, among biopsies of women who had cervical cancer. He went on to show that more than one HPV type could lead to cervical cancer, in part by cloning HPV 16 and another type, 18. Further research has shown that the two HPV types are consistently found in about 70 percent of cervical cancer biopsies throughout the world,[/quote]
All the newsreports used the Nobel Prize phrase that Zur Hausen, went against the "current dogma of the medical establishment" . [quote]His discovery has led to characterization of the natural history of HPV infection, an understanding of mechanisms of HPV-induced carcinogenesis and the development of prophylactic vaccines against HPV acquisition.[/quote] Note that it took 25 years before this doctor got his appropriate recognition. So mark your calendars for around 2033 to see when Dr. Gillison's and OCF's contributions are belatedly acknowledged.
charm


65 yr Old Frack
Stage IV BOT T3N2M0 HPV 16+
2007:72GY IMRT(40) 8 ERBITUX No PEG
2008:CANCER BACK Salvage Surgery
25GY-CyberKnife(5) 3 Carboplatin
Apaghia /G button
2012: CANCER BACK -left tonsilar fossa
40GY-CyberKnife(5) 3 Carboplatin

Passed away 4-29-13
Charm2017 #114362 03-20-2010 03:50 PM
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They can keep any acknowledgments .... I would just like to see something for those already exposed to protect them, or a means to break the cascade of events that leads to malignancy in those exposed once that sequence of events is discovered before a malignancy actually develops.

I forget where I found the original article about a French doc that first realized that cervical cancer was tied to sexual behavior. He noticed that prostitutes were often found with the disease, but nuns ( who practiced celibacy) never were, concluding that without sex, the unknown causative agent could not be transfered to someone.


Brian, stage 4 oral cancer survivor. OCF Founder and Director. The first responsibility of a leader is to define reality. The last is to say thank you. In between, the leader is a servant.
Brian Hill #114485 03-23-2010 06:39 PM
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Well, since my cancer was HPV-caused I guess I've lived life more like a prostitute than a nun....

D2


David 2
SCC of occult origin 1/09 (age 55)| Stage III TXN1M0 | HPV 16+, non-smoker, moderate drinker | Modified radical neck dissection 3/09 | 31 days IMRT finished 6/09 | Hit 14 years all clear in 6/23 | Radiation Fibrosis Syndrome kicked in a few years after treatment and has been progressing since | Prostate cancer diagnosis 10/18
David2 #114488 03-23-2010 07:00 PM
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Well, at least it means that like most adults, you have had sex at some point. This is not a virus that people are easily going to avoid, since it is so commonplace. There are just some of us, me included, that have an immune system that does not recognize it as a threat, or is unable to clear the infection.


Brian, stage 4 oral cancer survivor. OCF Founder and Director. The first responsibility of a leader is to define reality. The last is to say thank you. In between, the leader is a servant.
Brian Hill #114498 03-24-2010 05:12 AM
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D2,

You can have oral sex one time and contract HPV orally. You can french kiss one time and contract HPV orally.

Maybe you were just lucky?


David

Age 58 at Dx, HPV16+ SCC, Stage IV BOT+2 nodes, non smoker, casual drinker, exercise nut, Cisplatin x 3 & concurrent IMRT x 35,(70 Gy), no surgery, no Peg, Tx at Moffitt over Aug 06. Jun 07, back to riding my bike 100 miles a wk. Now doing 12 Spin classes and 60 outdoor miles per wk. Nov 13 completed Hilly Century ride for Cancer, 104 miles, 1st Place in my age group. Apr 2014 & 15, Spun for 9 straight hrs to raise $$ for YMCA's Livestrong Program. Certified Spin Instructor Jun 2014.
davidcpa #114512 03-24-2010 11:53 AM
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Darn! That ONE TIME... what were the odds?


David 2
SCC of occult origin 1/09 (age 55)| Stage III TXN1M0 | HPV 16+, non-smoker, moderate drinker | Modified radical neck dissection 3/09 | 31 days IMRT finished 6/09 | Hit 14 years all clear in 6/23 | Radiation Fibrosis Syndrome kicked in a few years after treatment and has been progressing since | Prostate cancer diagnosis 10/18
David2 #114527 03-24-2010 05:21 PM
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LOL No comment. I can't even count that high.


Since posting this. UPMC, Pittsburgh, Oct 2011 until Jan. I averaged about 2 to 3 surgeries a week there. w Can't have jaw made as bone is deteroriating steaily that is left in jaw. Mersa is to blame. Feeding tube . Had trach for 4mos. Got it out April.
--- Passed away 5/14/14, will be greatly missed by everyone here
EzJim #114550 03-24-2010 10:03 PM
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No comment necessary, Jim. All I have to do is read that "cancer free aug 08" at the bottom of your post and I break into a big smile.(to say nothing of your 100 weekly miles, fellow D!)

D2


David 2
SCC of occult origin 1/09 (age 55)| Stage III TXN1M0 | HPV 16+, non-smoker, moderate drinker | Modified radical neck dissection 3/09 | 31 days IMRT finished 6/09 | Hit 14 years all clear in 6/23 | Radiation Fibrosis Syndrome kicked in a few years after treatment and has been progressing since | Prostate cancer diagnosis 10/18
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