Hi Everyone,

I am new here, should post in here.

I have white lesion on left middle ( 1cm*1cm cycle shape )of my tongue for six months now.

I am 33, non-smoker or drinker. Feeling a little numb when touch it, but no pain.

I went to hospital and took biopsy.

Below is the report.

Leukoplakia oral cavity

Microscopic description

Section show two fragments of tongue mucosa including skeletal muscle. The surface squamous epithelium is mildly hyperplastic with a vascular core and shows surface colonisation by small yeast forms and bacteria. The lamina propria contains mild chronic inflammatory cells including lymphocytes and plasma cells with a lichenoid reaction patter. There is no evidence of dyplasia or malignancy

Diagnosis -Dorsal tongue biopsy :
Mild lichenoid reaction pattern ,Mild squamous hyperplasia and surface colonisation by bacteria and fungal yeast forms; negative for dysplasia

The hospital ENT specialist told me it is nothing worry about it ( when I collect the result from him ) and I need to keep eyes on it if it is going to be bigger or blooding.

I was asking him is there any treatment to cure the lesion and he said it will be on my tongue for years & no treatments!!

I am so concerned now as oral cancer is absolutely suffer for myself and my family.

Does anyone have any suggestion what I should do or find another specialist for re-check and seek any treatments?

Much appreciated.

Thanks,

Bill

Welcome to OCF. You are so very lucky to have received this report! It is NOT oral cancer. Count your blessings! Others with a similar diagnosis have had surgery to remove the lesion. I believe type or lesion has a high rate of return so it could always come back. A second opinion would be a good idea.

Best wishes!

Thanks Christine,

The lesion is still on my tongue as the ENT specialist did not ask to remove it, and leave as it is, which is make me more concerned.

I have read many posts and it has high risk to turn into cancer in 2 years� time ( maybe less ) if did not take any treatments.

Really need any suggestions for what I should do.

A second opinion with an ENT who specializes in oral cancer would be my suggestion.

Do keep an eye on it and definitely react quickly if you think there have been any changes.

Welcome.
Congrats on the report as it shows you negative for cancer. It does seem like this may be a precancerous condition so do watch for changes and have it checked out regularly.

Don

Thanks everyone,

I am going to see another specialist as I cannot let it leave there till turning into cancer.

I have a stupid question, is this lesion Leukoplakia or lichen planus based on my Diagnosis? Or they are the same thing.

They are two different things.

Let's set the record straight on leukoplakias going all the way to cancer. First white lesions are much less a threat than red ones. Leukoplakia about 25% of the time eventually converts to dysplasia, (a starting, measurable cell corruption that MIGHT continue to malignancy) and that is one step in the wrong direction. But remember it only happens 25% of the time. In all dysplastic cells you have low grade and high grade forms. Considering both types, only 25% of all dysplasia convert to malignancy. This is all out of Dr. Mark LIngen's papers who is a very highly regarded pathology researcher at UIC Chicago and an POCF advisory board member.

Yes you need to watch these things, particularly for any changes in them, but they are not wildly risky. If it starts to change I would have it burned off with a laser by an oral surgeon. It may or may not return, and it pretty much always does in tobacco users. That still doesn't mean that it progresses to cancer. There is no time period as suggested above for this to convert or do nothing. A leukoplakia could exist in you mouth for decades and do nothing. It could also grow and become dysplastic 25% of the time� but that it would do that in a 2 year time frame is a complete scientific unknown.

LIchen Planus is a different animal, it is an auto immune issue for which there is no real treatment, and does not convert to an oral cancer malignancy, though some SCC's have been found within an area of LP. That isn't the same thing as saying that LP converts to a malignancy. There is a difference between a correlation and a causation.

Your biopsy results are very clear that this is not a risky lesion, and that it has fungal qualities that can be treated and resolved. That makes this NOT leukoplakia, and a hyperplastic reaction to a fungal invasion.

Thanks Brian, this is very helpful! Will keep my eyes on it and hope its never happened. Cheers!