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#51570 06-24-2006 02:20 AM
Joined: Apr 2004
Posts: 837
"Above & Beyond" Member (300+ posts)
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"Above & Beyond" Member (300+ posts)

Joined: Apr 2004
Posts: 837
Herson,

From what I've seen here, there certainly do seem to be variations in the protocols for Stage II, often based on the results of pathology reports post-surgery. Although my margins were clean and there was no evidence of node involvement, the tumor itself was poorly differentiated, which means the tumor cells showed abnormalities that could cause them to grow more aggressively. (By contrast, we've had members here with well-differentiated Stage II tumors whose doctors did not recommend radiation.) I believe the "poorly differentiated" classification was a key factor that my doctors looked to in telling me I should have radiation. Since they didn't have that information until after the surgery, they couldn't give me a definitive answer on radiation prior to that. This may well be the case with your mother also.

Cathy


Tongue SCC (T2M0N0), poorly differentiated, diagnosed 3/89, partial glossectomy and neck dissection 4/89, radiation from early June to late August 1989
#51571 06-24-2006 03:29 AM
Joined: Feb 2005
Posts: 2,019
Patient Advocate (old timer, 2000 posts)
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Patient Advocate (old timer, 2000 posts)

Joined: Feb 2005
Posts: 2,019
And just as another example of that, I was stage II with perineural invasion (which means the tumor was growing along a nerve). Because there is some research showing that perineral invasion is a significant predictor of recurrences, that was a key factor in getting a recommendation for radiation and for chemo (although everyone agreed the chemo was an aggrissive treatment for my stage and I felt that part was really my choice). Perineural invasion was also something that couldn't be determined until after the surgery was done, so, like Cathy, I didn't get a definitive answer about radiation until after my surgery.

Nelie


SCC(T2N0M0) part.glossectomy & neck dissect 2/9/05 & 2/25/05.33 IMRT(66 Gy),2 Cisplatin ended 06/03/05.Stage I breast cancer treated 2/05-11/05.Surgery to remove esophageal stricture 07/06, still having dilatations to keep esophagus open.Dysphagia. "When you're going through hell, keep going"
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