| Joined: Dec 2003 Posts: 2,606 Likes: 2 Patient Advocate (old timer, 2000 posts) | Patient Advocate (old timer, 2000 posts) Joined: Dec 2003 Posts: 2,606 Likes: 2 | [quote=rosymonroe]I had the "3 big bag" Cisplatin and I guess looking at these post I was pretty lucky. Besides the extreme N&V after the first dose, nausea for a few days after the next 2 doses and the usually taste and lack of appetite problems and hair loss so far so good. As far as I can tell I have no lasting effects yet. I take that back, I get an occasional ringing in my ear, and I mean very occasional, maybe once a week for less than an hour. And I get a tingling in my left shoulder blade sometimes that the docs don't seem to think is connected to any of the treatment but it was never there before. [/quote]
It is from treatment and some from inactivity during treatment. The tingling and numbing is usually from vascular constriction and nerve impingement. Scalene muscle entanglement with the brachial plexus is instant relief for shoulder pain, numbness and tingling in limbs.
SCC Stage IV, BOT, T2N2bM0 Cisplatin/5FU x 3, 40 days radiation Diagnosis 07/21/03 tx completed 10/08/03 Post Radiation Lower Motor Neuron Syndrome 3/08. Cervical Spinal Stenosis 01/11 Cervical Myelitis 09/12 Thoracic Paraplegia 10/12 Dysautonomia 11/12 Hospice care 09/12-01/13. COPD 01/14 Intermittent CHF 6/15 Feeding tube NPO 03/16 VFI 12/2016 ORN 12/2017 Cardiac Event 06/2018 Bilateral VFI 01/2021 Thoracotomy Bilobectomy 01/2022 Bilateral VFI 05/2022 Total Laryngectomy 01/2023
| | | | Joined: May 2013 Posts: 134 Senior Member (100+ posts) | Senior Member (100+ posts) Joined: May 2013 Posts: 134 | Cisplatin x 3 here. Tinnitus got worse. No n & v that I can directly attribute to the cisplatin. Chemo was what I most feared going in and it was pretty anticlimatic. I was given the choice (cisplatin or Erbitux) and was told the "book" says cisplatin kills it every time. By "the book" I think he meant conventional wisdom and by every time I think he meant it was very successful. For me, he was right.
Dx March 2011 via FNA (49 yrs old) SCC BoT HPV+ exact strain unknown Stage IVa T3N2cM0 Cisplatin x 3, IMRT x 40 (7267 cGy) One node removed post-treatment (rad dmg) Clean PET 10/28/11 Swallow therapy | | | | Joined: Jul 2012 Posts: 3,267 Likes: 1 Patient Advocate (old timer, 2000 posts) | Patient Advocate (old timer, 2000 posts) Joined: Jul 2012 Posts: 3,267 Likes: 1 | I had TPF Induction Chemo, which is high doses of Cjsplatin 160mg, Taxotere 160mg, and 5-FU1600mg in five days. That put me in the hospital for 270 days. For my 2nd chemo, last October, I had Erbitux, and Taxore, which Taxotere was cut out the in the 4th week, due to worsening of the preexisting neuropathy, and was hospitalized for three days for blood transfusion due to low hemoglobin, dehydration.
10/09 T1N2bM0 Tonsil 11/09 Taxo Cisp 5-FU, 6 Months Hosp 01/11 35 IMRT 70Gy 7 Wks 06/11 30 HBO 08/11 RND PNI 06/12 SND PNI LVI 08/12 RND Pec Flap IORT 12 Gy 10/12 25 IMRT 50Gy 6 Wks Taxo Erbitux 10/13 SND 10/13 TBO/Angiograph 10/13 RND Carotid Remove IORT 10Gy PNI 12/13 25 Protons 50Gy 6 Wks Carbo 11/14 All Teeth Extract 30 HBO 03/15 Sequestromy Buccal Flap ORN 09/16 Mandibulectomy Fib Flap Sternotomy 04/17 Regraft hypergranulation Donor Site 06/17 Heart Attack Stent 02/19 Finally Cancer Free Took 10 yrs
| | | | Joined: Aug 2013 Posts: 23 Member | OP Member Joined: Aug 2013 Posts: 23 | Hello everyone, Thanks for the article Paul. According to the research article the Cisplatin once every 3 weeks was actually better in terms of less toxicity and adverse side effects than the lower dose every week.
In discussion with my Chemo oncologist, she wants to try a less concentrated (75 mg/m squared) once every 3 weeks approach during radiation. The therapy should begin next week, still waiting for the phone call from my Radiation oncologist.
Take care, Steve
6/5 ENT visit 6/11 FNA biopsy on lymph node 6/13 DX T2N2b stage 4 SCC on right tonsil metastasis to lymph nodes on right side 7/8 first chemo using Cetuximab 8/20 radiation oncologist initial visit 8/21 dental clearance Cisplatin and Radiation starting Sept 9
| | | | Joined: Aug 2012 Posts: 214 Likes: 1 Gold Member (200+ posts) | Gold Member (200+ posts) Joined: Aug 2012 Posts: 214 Likes: 1 | Good luck with treatment. Watch out for constipation. Cisplatin and/or anti nausia drugs really screw up the whole solids processing. Have a piece of paper by the medicine stash. Write down date, time, and drug. I found it very hard to remember what I took and when. Strap yourself in tight, the next 14 weeks are brutal. Have a driver on call at all time, you might not need them but its good to have. For me chemo days, driving was impossible.
But for me, 9 month out, the ligering side effects are just a mere inconvience. Although having to get only mild chicken wings at the bar is not quite the same.
Hockey Dad 43, No smoke, Small BOT HPV+16 8/30/12 Biopsy found SCC in Lymph node (removed) 9/19 DX 4a T1N2aM0 10/1 TX 2x Cisplatin 35 IMRT 70 gry (Done 11/15) PEG tube in 11/7. Out 1/4, Back at work 2/4/13 PET 2/13 Clear, 10/16 all Scopes Clear, 4/14 Chest X-ray Clear, 5/14 Abdominal ultrasound Clear, 8 yrs clean!!!
| | | | Joined: Apr 2013 Posts: 319 Platinum Member (300+ posts) | Platinum Member (300+ posts) Joined: Apr 2013 Posts: 319 | I had 8 weeks rads with the 3-bagger of Cisplatin. The Cisplatin kicked my butt everyway but loose. I lost 38 lbs in less than 90 days.
But - I drove myself to the hospital every day, even though I had to be very alert, looking for a place to pull over and call for my cousin, RALPH, if I ever went over that thin line between feeling like I'll lose it and actually losing it. Oddly, I never lost it on that drive, despite the fact that it was 24 miles each way.
I've experienced neuropathy with every bout of every form of chemo I had. I was warned to be alert to tingling in my toes or fingers and never experienced that. HOWEVER, I did get some dandy neuropathy in my toes, only because it feels like my toes are being crushed by a shoe that's too small, that's what I thought was going on. Surprise! It's annoying, but not the end of life as we know it.
As an old cannon-cocker and paratrooper, I'd lost a good deal of hearing range already. My tinnitus is always (still) around, but it comes in handy at night because when I tune it IN, it sounds like sitting at the edge of a clearing in a forest, complete with katydids, tree-frogs and crickets. Very relaxing!
Black clouds and silver linings, eh?
I've had some loss of fine resolution of feeling in my fingertips, but it's minor. Still, I have to be careful about holding folding money and trying to carry on a conversation, the paper slips out when I'm not concentrating on it, and I never know it.
So far, no damage to my "grin" muscles, thoug...
My intro: http://oralcancersupport.org/forums/ubbt...3644#Post16364409/09 - Dx OC Stg IV 10/09 - Chemo/3 Cisplatin, 40 rad 11/09 - PET CLEAN 07/11 - Dx Stage IV C. (Liver) 06/12 - PET CLEAN 09/12 - PET Dist Met (Liver) 04/13 - PET CLEAN 06/13 - PET Dist Met (Liver + 1 lymph node) 10/13 - PET - Xeloda ineffective 11/13 - Liver packed w/ SIRI-Spheres 02/14 - PET - Siri-Spheres effective, 4cm tumor in lymph-node 03/15 - Begin 15 Rads 03/24 - Final Rad! Woot! 7/27/14 Bart passed away. RIP!
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