My ENT uses the spray and I hate that stuff! She never really waits for it to kick in either. My RO doesn't use the spray at all because he says it narrows the nasal passages and makes it harder to get the scope down. My RO doesn't hurt when he scopes me, but my ENT kills me. I once got scoped by both of them about an hour apart (that was the last time I scheduled two doctors appointments on the same day!) and my RO got mad because my ENT used the spray when she scoped me and apparently he could still tell when he went to scope me. Oh the drama!