When I was on prescription pain meds, I had to take daily two "Senesol" pills ground up and put through the PEG--along with the occassional stool softener. But I didn't need the stool softener that often unless I forgot the Senesol pills for a day. My medical oncologist once said the three main problems with taking prescription pain meds for cancer are not addiction but "constipation, constipation and constipation". You have to stay really on top of it too in a daily way........