Well, the Zantac and Alegra have not had any affect at all so far. I had a pin head size cavity right next to an old filling that the dentist wanted to take care of in May. I've called and set the appointment to have it taken care of, but I'm also hoping to talk to him about the changes in my mouth, as they are much different than when he saw me in May. The appointment is set for 4 days ahead of my follow up ESR test. Hopefully a second set of eyes from a doctor I've been seeing for 8 years will help me one way or the other.