Besides all the above remedies for constipation, my oncology nursed suggested that I "drink" from my tube at least 10 LARGE glasses of water a day to help with both my hydration problem and constipation. Seems like I spent a fair amount of time on the pot, but it kept me out of the hospital and for that I was always grateful. Boy, if it ain't one thing, its another....seems like that anyway when you're going through treatment. After I finished treatment I remember feeling worse than ever when I thought I should be feeling better. I hope your sister begins to feel better soon; she will, but it does take time. Sincerely, Donna