Peter --

In that first biopsy report, "reactive change" indicates that there is a minor change in the appearance of some of the cells. The "reactive change" could simply be due to the inflammation noted.

The term "squamous mucosa" refers ONLY to the type and location of cells examined, and has nothing to do with whether cancer is present.

From the National Cancer Institute's dictionary of cancer-related terms, found at http://www.cancer.gov/dictionary/ :

squamous cell: Flat cell that looks like a fish scale under a microscope. These cells cover inside and outside surfaces of the body. They are found in the tissues that form the surface of the skin, the lining of the hollow organs of the body (such as the bladder, kidney, and uterus), and the passages of the respiratory and digestive tracts.

mucosa: The moist, inner lining of some organs and body cavities (such as the nose, mouth, lungs, and stomach). Glands in the mucosa make mucus (a thick, slippery fluid). Also called mucous membrane.

As for your newest biopsy report: At least you now know for certain what you are dealing with. Seeing the experts at Shands is the prudent thing to do. Your doctor can refer you, or you can call them yourself.

-- Leslie


Leslie

April 2006: Husband dx by dentist with leukoplakia on tongue. Oral surgeon's biopsy 4/28/06: Moderate dysplasia; pathology report warned of possible "skip effect." ENT's excisional biopsy (got it all) 5/31/06: SCC in situ/small bit superficially invasive. Early detection saves lives.