My worst nightmare has become my reality. His most recent scan showed metastasis to his lungs. There are several lesions and they are located all over so operation is not an option. He is beginning a new trial, still in Phase 1. It is a study combining the drugs Recombinant Interleukin-21, riL21 and Anti-PD-1. The two drugs have been studied alone, but never together. Does anyone have any info on this study? When we went to sign the consent, she was very vague on the success of each drug by itself and wouldn't reveal any info on how the patients that are in the first 2 cohorts have responded. The lesions have grown within the last couple weeks. I'm scared and looking for advice...
Thanks!


Caregiver to SO, Ari-52 yrs.
6/2008:Stage IV SCC BOT+MET neck HPV +
8/2008:TX TORS+RND+RAD+PEG
6/2011:Stage IV Laryngeal TX chemo+RAD
he had 2 Rec to nodes in neck RX RAD
6/2012:Total Laryngectomy
9/2012: DX Hypopharyngeal cancer stage IV TX 3 Chemo,Erbitux
3/2013: MET LUNGS begins trial 3/11/13