only one - you've just had the most harrowing year of your life and you are questioning whether or not you should enjoy an occasional drink?

But seriously, there are studies out there that suggest that heavy drinking in tandem with smoking is a very very bad idea. I have also read a review (sorry can't find it now) that suggests that heavy drinking (daily consumption of 4 standard drinks or more) is independently associated with oral cancer. I haven't read anything that suggests an occasional drink does anything other than make you feel good.