Susan

I was not in a clinical trial but did have the full 8 Erbitux treatments. IMO, Erbitux is like that nursery rhyme: [quote]When it's good, it's very very good, and when it's bad, it's horrid.[/quote] You will probably need to have someone drive you to and from the chemo TX for at least the last 4 so bear that in mind in making your decision.

My feelings are mixed on Erbitux as it did not stop my cancer from coming back and my MO decided that my tumor was resistant to Erbitux so the second time around switched me to Cisplatin. I never got the "acne rash" but I did have the worst case of radiation dermatitis my CCC has ever seen as a result of the Erbitux. That is a worse case scenario as none of the other patients getting it in my waiting room had more than the acne rash.

I was ecstatic when I was told I would not have to do the platinum based chemos and could use the new wonder drug Erbitux. Subsequently they have discovered that Erbitux simply does not work for colon cancer with some people due to their genetics. While there remains some scientific controversy on this, assessment for EGFR expression is now required for use in colorectal cancer, but not in head & neck cancer. IMO, there is a similar mechanism for head & neck cancer but there are no biomarkers or tests yet to determine the unfortunate minority like myself for which Erbitux does not work.

The odds are it will work for you, so go for it.
Charm


65 yr Old Frack
Stage IV BOT T3N2M0 HPV 16+
2007:72GY IMRT(40) 8 ERBITUX No PEG
2008:CANCER BACK Salvage Surgery
25GY-CyberKnife(5) 3 Carboplatin
Apaghia /G button
2012: CANCER BACK -left tonsilar fossa
40GY-CyberKnife(5) 3 Carboplatin

Passed away 4-29-13