I wish I had the answers to the questions that you have. I do not know about the margins- only that the trace in the blood was so low that is was not numbered. His doctors highly recommended radiation and intravenous chemo- Brian alone is making this decision. They told him there was a 30% chance that Methotrexate alone would work. He finally broke down today and said that he "May" agree to a single radiation treatment that the doctors said would "flash" the methotrexate and jump start his current treatment plan. He finally did share his illness with one other friend today- our vetinarian who is also a personal friend and cancer survivor- so I have someone who I can turn to a little. Thanks for your questions and effort in helping me through this. Teresa